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1

Cardiac expression and location of hexokinase changes in a mouse model of pure creatine-deficiency

Branovets, Jelena, Karro, Niina, Barsunova, Karina, Laasmaa, Martin, Lygate, Craig A., Vendelin, Marko, Birkedal, Rikke

Journal:

American journal of physiology. Heart and circulatory physiology

Year:

2020

File:

PDF, 865 KB

2020

2

Fast, high-resolution in vivo cine magnetic resonance imaging in normal and failing mouse hearts on a vertical 11.7 T system

Jürgen E. Schneider, Paul J. Cassidy, Craig Lygate, Damian J. Tyler, Frank Wiesmann, Stuart M. Grieve, Karen Hulbert, Kieran Clarke, Stefan Neubauer

Journal:

Journal of Magnetic Resonance Imaging

Year:

2003

Language:

english

File:

PDF, 1.06 MB

english, 2003

3

Assessment of motion gating strategies for mouse magnetic resonance at high magnetic fields

Paul J. Cassidy, Jürgen E. Schneider, Stuart M. Grieve, Craig Lygate, Stefan Neubauer, Kieran Clarke

Journal:

Journal of Magnetic Resonance Imaging

Year:

2004

Language:

english

File:

PDF, 1.07 MB

english, 2004

4

Accelerating cine-MR imaging in mouse hearts using compressed sensing

Tobias Wech, Angela Lemke, Debra Medway, Lee-Anne Stork, Craig A. Lygate, Stefan Neubauer, Herbert Köstler, Jürgen E. Schneider

Journal:

Journal of Magnetic Resonance Imaging

Year:

2011

Language:

english

File:

PDF, 952 KB

english, 2011

5

Ultra-fast and accurate assessment of cardiac function in rats using accelerated MRI at 9.4 Tesla

Jürgen E. Schneider, Titus Lanz, Hannah Barnes, Debra Medway, Lee-Anne Stork, Craig A. Lygate, Sean Smart, Mark A. Griswold, Stefan Neubauer

Journal:

Magnetic Resonance in Medicine

Year:

2008

Language:

english

File:

PDF, 786 KB

english, 2008

6

Accelerated cardiac magnetic resonance imaging in the mouse using an eight-channel array at 9.4 Tesla

Jürgen E. Schneider, Titus Lanz, Hannah Barnes, Lee-Anne Stork, Steffen Bohl, Craig A. Lygate, Roger J. Ordidge, Stefan Neubauer

Journal:

Magnetic Resonance in Medicine

Year:

2011

Language:

english

File:

PDF, 631 KB

english, 2011

7

Improved method for quantification of regional cardiac function in mice using phase-contrast MRI

Erica Dall'Armellina, Bernd A. Jung, Craig A. Lygate, Stefan Neubauer, Michael Markl, Jürgen E. Schneider

Journal:

Magnetic Resonance in Medicine

Year:

2012

Language:

english

File:

PDF, 3.36 MB

english, 2012

8

Changes in creatine transporter function during cardiac maturation in the rat

Alexandra Fischer, Michiel ten Hove, Liam Sebag-Montefiore, Helga Wagner, Kieran Clarke, Hugh Watkins, Craig A Lygate, Stefan Neubauer

Journal:

BMC Developmental Biology

Year:

2010

Language:

english

File:

PDF, 801 KB

english, 2010

9

Cardiac structure and function during ageing in energetically compromised Guanidinoacetate N-methyltransferase (GAMT)-knockout mice – a one year longitudinal MRI study

Jürgen E Schneider, Lee-Anne Stork, Jordana T Bell, Michiel ten Hove, Dirk Isbrandt, Kieran Clarke, Hugh Watkins, Craig A Lygate, Stefan Neubauer

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2008

Language:

english

File:

PDF, 1.02 MB

english, 2008

10

T2-mapping of ischaemia/reperfusion-injury in the in vivo mouse heart

Steffen Bohl, Craig A Lygate, Jeanette Schulz-Menger, Stefan Neubauer, Jurgen E Schneider

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2010

Language:

english

File:

PDF, 868 KB

english, 2010

11

Accelerating global left-ventricular function assessment in mice using reduced slice acquisition and three-dimensional guide-point modelling

Alistair A Young, Debra J Medway, Craig A Lygate, Stefan Neubauer, Jürgen E Schneider

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2011

Language:

english

File:

PDF, 562 KB

english, 2011

12

Accurate infarct-size measurements from accelerated, compressed sensing reconstructed cine-MRI images in mouse hearts

Tobias Wech, Debra Medway, Craig A Lygate, Stefan Neubauer, Herbert Köstler, Jurgen E Schneider

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2012

Language:

english

File:

PDF, 137 KB

english, 2012

13

Highly accelerated cardiac functional MRI in rodent hearts using compressed sensing and parallel imaging at 9.4T

Tobias Wech, Craig A Lygate, Stefan Neubauer, Herbert Köstler, Jurgen E Schneider

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2012

Language:

english

File:

PDF, 199 KB

english, 2012

14

Long-term stability of cardiac function in normal and chronically failing mouse hearts in a vertical-bore MR system

Jürgen E. Schneider, Karen J. Hulbert, Craig A. Lygate, Michiel Ten Hove, Paul J. Cassidy, Kieran Clarke, Stefan Neubauer

Journal:

Magnetic Resonance Materials in Physics, Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 416 KB

english, 2004

15

Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age

Lygate, Craig A., Medway, Debra J., Ostrowski, Philip J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Hunyor, Imre, Zervou, Sevasti, Schneider, Jurgen E., Neubauer, Stefan

Journal:

Basic Research in Cardiology

Year:

2012

Language:

english

File:

PDF, 470 KB

english, 2012

16

1H-MR spectroscopy for analysis of cardiac lipid and creatine metabolism

Faller, Kiterie M. E., Lygate, Craig A., Neubauer, Stefan, Schneider, Jürgen E.

Journal:

Heart Failure Reviews

Year:

2013

Language:

english

File:

PDF, 490 KB

english, 2013

17

Mechanisms of creatine depletion in chronically failing rat heart

Michiel Ten Hove, Sharon Chan, Craig Lygate, Mina Monfared, Ernest Boehm, Karen Hulbert, Hugh Watkins, Kieran Clarke, Stefan Neubauer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2005

Language:

english

File:

PDF, 132 KB

english, 2005

18

Supra-normal (phospho-)creatine levels lead to heart failure in mice overexpressing the cardiac creatine transporter—a longitudinal study

Michiel ten Hove, Darci Phillips, Julie Wallis, Craig A. Lygate, Alexandra Fischer, Liam Sebag-Montefiore, Dana Dawson, Karen Hulbert, Wen Zhang, Hugh Watkins, Kieran Clarke, Jürgen E. Schneider, Stef

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

19

The creatine kinase energy transport system in the failing mouse heart

Craig A. Lygate, Alexandra Fischer, Liam Sebag-Montefiore, Julie Wallis, Stefan Neubauer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

20

HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation

Carsten Willam, Patrick H. Maxwell, Lynn Nichols, Craig Lygate, Ya Min Tian, Wanja Bernhardt, Michael Wiesener, Peter J. Ratcliffe, Kai-Uwe Eckardt, Christopher W. Pugh

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2006

Language:

english

File:

PDF, 1.62 MB

english, 2006

21

The creatine kinase energy transport system in the failing mouse heart

Craig A. Lygate, Alexandra Fischer, Liam Sebag-Montefiore, Julie Wallis, Michiel ten Hove, Stefan Neubauer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

22

Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart

Andrew J. Murray, Mark A. Cole, Craig A. Lygate, Carolyn A. Carr, Daniel J. Stuckey, Sarah E. Little, Stefan Neubauer, Kieran Clarke

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 459 KB

english, 2008

23

Creatine uptake in mouse hearts with genetically altered creatine levels

Michiel ten Hove, Kimmo Makinen, Liam Sebag-Montefiore, Imre Hunyor, Alexandra Fischer, Julie Wallis, Dirk Isbrandt, Craig Lygate, Stefan Neubauer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 528 KB

english, 2008

24

Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background

Craig A. Lygate, Imre Hunyor, Debra Medway, Joe P. de Bono, Dana Dawson, Julie Wallis, Liam Sebag-Montefiore, Stefan Neubauer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2009

Language:

english

File:

PDF, 424 KB

english, 2009

25

Mice over-expressing the myocardial creatine transporter develop progressive heart failure and show decreased glycolytic capacity

Darci Phillips, Michiel ten Hove, Jurgen E. Schneider, Colin O. Wu, Liam Sebag-Montefiore, Angel M. Aponte, Craig A. Lygate, Julie Wallis, Kieran Clarke, Hugh Watkins, Robert S. Balaban, Stefan Neubau

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 815 KB

english, 2010

26

Surgical models of hypertrophy and heart failure: Myocardial infarction and transverse aortic constriction

Journal:

Drug Discovery Today: Disease Models

Year:

2006

Language:

english

File:

PDF, 783 KB

english, 2006

27

Heart Failure and Altered Cardiac Energetics—A New Mouse Model for Inducible Sarcomeric Mitochondrial Creatine Kinase (Mt-CK)

Imre Hunyor, Kimmo Makinen, Ben Davies, Debra Medway, Craig Lygate, Dirk Isbrandt, Stefan Neubauer

Journal:

Heart Lung & Circulation

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

28

Unchanged Mitochondrial Organization and Compartmentation in Creatine Deficient GAMT-/- Mouse Heart

Branovets, Jelena, Sepp, Mervi, Kotlyarova, Svetlana, Jepihhina, Natalja, Sokolova, Niina, Aksentijevic, Dunja, Lygate, Craig A., Neubauer, Stefan, Vendelin, Marko, Birkedal, Rikke

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 57 KB

english, 2013

29

Metabolic Inflexibility of Malonyl CoA Decarboxylase (MCD) Knockout Mice Leads to Cardiac Remodelling and High Mortality During Peri-Weaning Period

Aksentijevic, Dunja, Medway, Debra J., Sebag-Montefiore, Liam, Zervou, Sevasti, Douglas, Gillian, Lopaschuk, Gary D., Neubauer, Stefan, Lygate, Craig A.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

30

Cardiomyocytes from Creatine-Deficient Mice Lacking L-Arginine:Glycine Amidinotransferase (AGAT) Show No Changes in Mitochondrial Organization and Cellular Compartmentation

Kotlyarova, Svetlana, Mandel, Merle, Sokolova, Niina, Aksentijevic, Dunja, Lygate, Craig A., Neubauer, Stefan, Vendelin, Marko, Birkedal, Rikke

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 40 KB

english, 2013

31

High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes

Aksentijević, Dunja, Lygate, Craig A., Makinen, Kimmo, Zervou, Sevasti, Sebag-Montefiore, Liam, Medway, Debra, Barnes, Hannah, Schneider, Jurgen E., Neubauer, Stefan

Journal:

European Journal of Heart Failure

Year:

2010

Language:

english

File:

PDF, 315 KB

english, 2010

32

Investigating cardiac energetics in heart failure

Lygate, Craig A., Schneider, Jürgen E., Neubauer, Stefan

Journal:

Experimental Physiology

Year:

2013

Language:

english

File:

PDF, 210 KB

english, 2013

33

A requirement for Gch1 and tetrahydrobiopterin in embryonic development

Douglas, Gillian, Hale, Ashley B., Crabtree, Mark J, Ryan, Brent J., Hansler, Alex, Watschinger, Katrin, Gross, Steven S, Lygate, Craig A., Alp, Nicholas J., Channon, Keith M.

Journal:

Developmental Biology

Year:

2015

Language:

english

File:

PDF, 4.79 MB

english, 2015

34

CINE-MR Imaging of the Normal and Infarcted Rat Heart Using an 11.7 T Vertical Bore MR System

Tyler, Damian, Lygate, Craig, Schneider, Jürgen, Cassidy, Paul, Neubauer, Stefan, Clarke, Kieran

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2006

Language:

english

File:

PDF, 9.39 MB

english, 2006

35

How to Perform an Accurate Assessment of Cardiac Function in Mice using High-Resolution Magnetic Resonance Imaging

Schneider, Jürgen, Wiesmann, Frank, Lygate, Craig, Neubauer, Stefan

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2006

Language:

english

File:

PDF, 334 KB

english, 2006

36

A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy

Ashrafian, Houman, Docherty, Louise, Leo, Vincenzo, Towlson, Christopher, Neilan, Monica, Steeples, Violetta, Lygate, Craig A., Hough, Tertius, Townsend, Stuart, Williams, Debbie, Wells, Sara, Norris,

Journal:

Year:

2010

Language:

english

File:

PDF, 6.68 MB

english, 2010

37

MLP accumulation and remodelling in the infarcted rat heart

Wilding, James R., Lygate, Craig A., Davies, Kay E., Neubauer, Stefan, Clarke, Kieran

Journal:

European Journal of Heart Failure

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

38

Refinement of analgesia following thoracotomy and experimental myocardial infarction using the Mouse Grimace Scale

Faller, Kiterie M. E., McAndrew, Debra J., Schneider, Jurgen E., Lygate, Craig A.

Journal:

Experimental Physiology

Year:

2015

Language:

english

File:

PDF, 435 KB

english, 2015

39

Proteomic and metabolomic changes driven by elevating myocardial creatine suggest novel metabolic feedback mechanisms

Zervou, Sevasti, Yin, Xiaoke, A. Nabeebaccus, Adam, O’Brien, Brett A., L. Cross, Rebecca, McAndrew, Debra J., Atkinson, R. Andrew, Eykyn, Thomas R., Mayr, Manuel, Neubauer, Stefan, Lygate, Craig A.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.80 MB

english, 2016

40

Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats

Brosnan, M. Julia, Hamilton, Carlene A., Graham, Delyth, Lygate, Craig A., Jardine, Emma, Dominiczak, Anna F.

Journal:

Journal of Hypertension

Year:

2002

Language:

english

File:

PDF, 2.30 MB

english, 2002

41

Compressed sensing to accelerate magnetic resonance spectroscopic imaging: evaluation and application to 23Na-imaging of mouse hearts

Maguire, Mahon L., Geethanath, Sairam, Lygate, Craig A., Kodibagkar, Vikram D., Schneider, Jürgen E.

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

42

Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice

Smart, Nicola, Riegler, Johannes, Turtle, Cameron W., Lygate, Craig A., McAndrew, Debra J., Gehmlich, Katja, Dubé, Karina N., Price, Anthony N., Muthurangu, Vivek, Taylor, Andrew M., Lythgoe, Mark F.,

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2017

Language:

english

File:

PDF, 1.71 MB

english, 2017

43

Resolving Fine Cardiac Structures in Rats with High-Resolution Diffusion Tensor Imaging

Teh, Irvin, McClymont, Darryl, Burton, Rebecca A. B., Maguire, Mahon L., Whittington, Hannah J., Lygate, Craig A., Kohl, Peter, Schneider, Jürgen E.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 4.13 MB

english, 2016

44

Dietary Supplementation with Homoarginine Preserves Cardiac Function in a Murine Model of Post-Myocardial Infarction Heart Failure

Atzler, Dorothee, McAndrew, Debra J., Cordts, Kathrin, Schneider, Jürgen E., Zervou, Sevasti, Schwedhelm, Edzard, Neubauer, Stefan, Lygate, Craig A.

Journal:

Year:

2017

Language:

english

File:

PDF, 143 KB

english, 2017

45

Metabolic arithmetic – do two wrongs make a right?

Lygate, Craig A.

Journal:

Cardiovascular Research

Year:

2017

Language:

english

File:

PDF, 684 KB

english, 2017

46

Metabolic remodelling in hypertrophied and failing myocardium: a review

Peterzan, Mark Andrew, Lygate, Craig A., Neubauer, Stefan, Rider, Oliver

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2017

Language:

english

File:

PDF, 1.14 MB

english, 2017

47

222 Augmentation of creatine kinase in vitro protects against simulated ischaemia reperfusion injury

Zervou, Sevasti, Whittington, Hannah J, Ostrowski, Philip J, Cao, Fang, Tyler, Jack, Lake, Hannah A, Neubauer, Stefan, Lygate, Craig A

Journal:

Year:

2017

Language:

english

File:

PDF, 63 KB

english, 2017

48

200 Nitric oxide promotes insulin-independent glucose uptake and preserves cardiac function and energetics in diabetes

Ziberna, Klemen, Duglan, Drew, Mafrici, Simona, Simon, Jillian, Lygate, Craig, Channon, Keith, Casadei, Barbara, Carnicer, Ricardo

Journal:

Year:

2017

Language:

english

File:

PDF, 77 KB

english, 2017

49

Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II–Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic Aneurysm

Chuaiphichai, Surawee, Rashbrook, Victoria S., Hale, Ashley B., Trelfa, Lucy, Patel, Jyoti, McNeill, Eileen, Lygate, Craig A., Channon, Keith M., Douglas, Gillian

Journal:

Year:

2018

Language:

english

File:

PDF, 1.81 MB

english, 2018

50

A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism

Stockebrand, Malte, Sasani, Ali, Das, Devashish, Hornig, Sönke, Hermans-Borgmeyer, Irm, Lake, Hannah A., Isbrandt, Dirk, Lygate, Craig A., Heerschap, Arend, Neu, Axel, Choe, Chi-Un

Journal:

Frontiers in Physiology

Year:

2018

Language:

english

File:

PDF, 3.77 MB

english, 2018

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